FREE SHIPPING ON ORDERS OVER $25
100% MONEY-BACK GUARANTEE
NO NSAIDS. NOT GREASY.
91,000+ FIVE-STAR REVIEWS
BUNDLE & SAVE
FREE SHIPPING ON ORDERS OVER $25
100% MONEY-BACK GUARANTEE
NO NSAIDS. NOT GREASY.
91,000+ FIVE-STAR REVIEWS
BUNDLE & SAVE
FREE SHIPPING ON ORDERS OVER $25
100% MONEY-BACK GUARANTEE
NO NSAIDS. NOT GREASY.
91,000+ FIVE-STAR REVIEWS
BUNDLE & SAVE
FREE SHIPPING ON ORDERS OVER $25
100% MONEY-BACK GUARANTEE
NO NSAIDS. NOT GREASY.
91,000+ FIVE-STAR REVIEWS
BUNDLE & SAVE
FREE SHIPPING ON ORDERS OVER $25
100% MONEY-BACK GUARANTEE
NO NSAIDS. NOT GREASY.
91,000+ FIVE-STAR REVIEWS
BUNDLE & SAVE
FREE SHIPPING ON ORDERS OVER $25
100% MONEY-BACK GUARANTEE
NO NSAIDS. NOT GREASY.
91,000+ FIVE-STAR REVIEWS
BUNDLE & SAVE
FREE SHIPPING ON ORDERS OVER $25
100% MONEY-BACK GUARANTEE
NO NSAIDS. NOT GREASY.
91,000+ FIVE-STAR REVIEWS
BUNDLE & SAVE
FREE SHIPPING ON ORDERS OVER $25
100% MONEY-BACK GUARANTEE
NO NSAIDS. NOT GREASY.
91,000+ FIVE-STAR REVIEWS
BUNDLE & SAVE
Penetrex's Advanced Pain Relief Cream Sold Out 12x Last Year — Save Up To 60% Today!
Get Instant Relief from Pain Discomfort or Your Money Back
Fast-acting OTC pain relief. 5% Menthol on top of the proven Penetrex formula 2 million+ people reorder. Built for the moment pain strikes. 100% money-back guarantee
CHOOSE YOUR PACKAGE
Couldn't load pickup availability
LOW STOCK | 324 TUBES SOLD TODAY!
- American express payment method
- Apple pay payment method
- Bancontact payment method
- Diners club payment method
- Discover payment method
- Google pay payment method
- Ideal payment method
- Master payment method
- Paypal payment method
- Shopify pay payment method
- Visa payment method
About Our Advanced Joint & Muscle Pain Relief Cream
OTC Pain Relief for Back, Knee, Shoulder, Neck & Hand Pain — Non-NSAID Formula
OTC Pain Relief for Back, Knee, Shoulder, Neck & Hand Pain — Non-NSAID Formula
5% Menthol is an OTC monograph active ingredient for the temporary relief of minor aches and pains of muscles and joints — including those associated with arthritis, simple backache, strains, sprains, and bruises. Apply it to the area that hurts. Within seconds, the cooling onset begins. That's not a sensation trick — that's the active ingredient working. Nothing enters your stomach. No GI irritation. No NSAIDs.
Built for Flare-Ups: Arthritis, Backache, Strains, Bruises & Sprains
Built for Flare-Ups: Arthritis, Backache, Strains, Bruises & Sprains
Penetrex Advanced is built for the moments pain spikes — the morning your back won't cooperate, the 2am knee throb, the post-shift shoulder that needs relief now. Use it for the temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backache, strains, bruises, and sprains. For ongoing daily support, the same formula compounds with consistent use.
Professional-Grade Formula: 5% Menthol + Arnica, MSM, Vitamin B6 & Boswellia
Professional-Grade Formula: 5% Menthol + Arnica, MSM, Vitamin B6 & Boswellia
Most OTC pain creams stop at the active ingredient. We didn't. Penetrex Advanced gives you 5% Menthol — at a higher concentration than most competitors (3%) — plus the four-ingredient formula 2 million+ people already trust: Arnica for topical soothing, Vitamin B6 for skin health, MSM for area conditioning, and Boswellia Serrata for a calming experience. Five pathways. One cream. Made in the USA.
Fast-Absorbing, Non-Greasy — Clean Menthol Scent, Not Locker-Room
Fast-Absorbing, Non-Greasy — Clean Menthol Scent, Not Locker-Room
Apply it and the cooling onset hits within seconds. No greasy film. No white cast. No stained sheets or scrubs. The menthol scent is intentionally clean and subtle — nothing like the aggressive blast from old-school sports creams. Use it before work, before a meeting, or in bed. The sensation does its job. The smell doesn't announce it to the room.
Trusted by Over 2+ Million Users and Made in USA
Trusted by Over 2+ Million Users and Made in USA
With a loyal customer base spanning over a decade, Penetrex has become a household name for natural topical support. Manufactured in the USA following strict quality standards, and suitable for those seeking vegan-friendly, paraben-free formulations.

Based on 91,028+ Real Reviews
Rated Excellent 4.9 / 5
Have Questions? We Have Answers.
Everything you need to know about common questions about our products and services.
-
Apply PENETREX® liberally to the affected area(s) and continue to massage in thoroughly for a minute or two until you can see that it has been absorbed through the skin. The appropriate amount of PENETREX® to use on each occasion should be enough so that the product massages in smoothly & comfortably over the entire area.
Repeat this 3 to 4 times per day over an initial period of at least 7 to 10 days and thereafter on an as needed basis.
As symptoms improve, reduce the frequency of applications accordingly to maintain relief and as a preventative measure. Many users have reported that over time PENETREX® provides them with more "efficient" results...requiring fewer applications while achieving quicker and more predictable results. -
We have customers who call or e-mail us the next day after they start using PENETREX® and they express disbelief at how quickly it provided them with relief.
At the same time, we also have customers who report back to us that they had begun to lose faith having used the product for a couple of weeks before they finally turned the corner. -
We utilize Amazon Prime's shipping, so your item should be shipped within the next business day and arrive within 2-8 business days depending on your area.
-
With over 2 Million+ jars of PENETREX® having been distributed since it was introduced, there have been no reports of recurring incidents which would indicate a common occurrence of any negative reaction to the product.
This is not surprising since all of the ingredients (see below) in PENETREX® are extremely well known and have been widely accepted by medical practitioners.
PENETREX® Cream Ingredient List: Water (Aqua), Arnica Montana Flower Extract, Helianthus Annuus (Sunflower) Seed Oil, Glycerin, Glyceryl Stearate, PEG-100 Stearate, Cetyl Esters, Steareth-20, Pyridoxine Hydrochloride (Vitamin B6), Methylsulfonylmethane (MSM/DMSO2), Glucosamine (Vegetable Source), Bilineurine Bitartrate, Ethoxydiglycol, Methyl Gluceth-20, Cetyl Myristoleate, Aloe Barbadensis (Aloe Vera) Leaf Extract, Butyrospermum Parkii (Shea Butter), Boswellia Serrata (Frankincense) Oil, Mentha Piperita (Peppermint) Oil, Cinnamomum Camphora (Camphor), Melaleuca Alternifolia (Tea Tree) Leaf Oil, Tocopherol (Vitamin E), Dipotassium Glycyrrhizinate, Dimethicone, Ammonium Acryloyl-Dimethyltaurate/VP Copolymer, Phenoxyethanol, DMDM Hydantoin, Iodopropynyl Butylcarbamate
PENETREX® Roll-On Gel Ingredient List: Water (Aqua), Isopropyl Alcohol, Arnica Montana Flower Extract, Pyridoxine Hydrochloride, Methylsulfonylmethane (MSM/DMSO2), Glucosamine (vegetable source), Bilineurine Bitartrate, Ethoxydiglycol, Cetyl Myristoleate, Aloe Barbadensis (Aloe Vera) Leaf Extract, Boswellia Serrata (Frankincense) Oil, Rosmarinus Officinalis (Rosemary) Oil, Juniperus Communis (Juniper Berry) Oil, Mentha Piperita (Peppermint) Oil, Eucalyptus Globulus (Eucalyptus) Leaf Oil, Melaleuca Alternifolia (Tee Tree) Leaf Oil, Cinnamomum Camphora (Camphor), Tocopherol (Vitamin E), Dipotassium Glycyrrhizinate, Carbomer, Triethanolamine, DMDM Hydantoin, Diazolidinyl Urea, Iodopropynyl Butylcarbamate -
PENETREX® Cream Ingredient List: Water (Aqua), Arnica Montana Flower Extract, Helianthus Annuus (Sunflower) Seed Oil, Glycerin, Glyceryl Stearate, PEG-100 Stearate, Cetyl Esters, Steareth-20, Pyridoxine Hydrochloride (Vitamin B6), Methylsulfonylmethane (MSM/DMSO2), Glucosamine (Vegetable Source), Bilineurine Bitartrate, Ethoxydiglycol, Methyl Gluceth-20, Cetyl Myristoleate, Aloe Barbadensis (Aloe Vera) Leaf Extract, Butyrospermum Parkii (Shea Butter), Boswellia Serrata (Frankincense) Oil, Mentha Piperita (Peppermint) Oil, Cinnamomum Camphora (Camphor), Melaleuca Alternifolia (Tea Tree) Leaf Oil, Tocopherol (Vitamin E), Dipotassium Glycyrrhizinate, Dimethicone, Ammonium Acryloyl-Dimethyltaurate/VP Copolymer, Phenoxyethanol, DMDM Hydantoin, Iodopropynyl Butylcarbamate
PENETREX® Roll-On Ingredient List: Water (Aqua), Isopropyl Alcohol, Arnica Montana Flower Extract, Pyridoxine Hydrochloride, Methylsulfonylmethane (MSM/DMSO2), Glucosamine (vegetable source), Bilineurine Bitartrate, Ethoxydiglycol, Cetyl Myristoleate, Aloe Barbadensis (Aloe Vera) Leaf Extract, Boswellia Serrata (Frankincense) Oil, Rosmarinus Officinalis (Rosemary) Oil, Juniperus Communis (Juniper Berry) Oil, Mentha Piperita (Peppermint) Oil, Eucalyptus Globulus (Eucalyptus) Leaf Oil, Melaleuca Alternifolia (Tee Tree) Leaf Oil, Cinnamomum Camphora (Camphor), Tocopherol (Vitamin E), Dipotassium Glycyrrhizinate, Carbomer, Triethanolamine, DMDM Hydantoin, Diazolidinyl Urea, Iodopropynyl Butylcarbamate
-
Most customers find that using PENETREX® on its own as directed provides the benefits and relief they desire.
Nevertheless, PENETREX® is currently being incorporated into overall therapy programs by end users as well as medical professionals worldwide who have found it to be an excellent compliment to other approaches including oral medications & prescriptions, orthopedic products, physical therapy and ultrasound.
PENETREX® is a product that allows each individual to develop their own regimen that works best for them...on its own or as an invaluable member of a multi-faceted approach. -
Absolutely Not. PENETREX® is lightly infused with a natural Chamomile Oil extract resulting in a pleasant yet hardly noticeable fragrance that vanishes completely after a minute or two.
PENETREX® is Non-Greasy, Non-Staining, Paraben-Free, Made in the USA & NEVER Tested on Animals -
PENETREX® was researched & developed by a renowned Chemist in Southern California.
PENETREX® is available to people worldwide, exclusively through Biomax Health Products, Inc. of San Diego, California. You may order it here on www.penetrex.com, on Amazon.com or you may wish to use our handy Store Locator Tool to find a retailer near you. PENETREX® is now available in over 12,000 Retail Locations.
With little to no advertising but strictly through word of mouth referrals and the Internet, Hundreds of Thousands of people from over 80 countries have been introduced to this product with great satisifaction.
Ask your Doctor/Physical Therapist/Chiropractor, etc. if they are familiar with PENETREX®. If they are not and would like to learn more about the product, please feel free to have them contact us. We can answer any questions they may have about incorporating PENETREX® into their practice.
-
YES. Your PENETREX® Purchase & Complete Satisfaction is Unconditionally Guaranteed by Biomax Health Products, Inc.. If you are less than 100% Satisfied with PENETREX® for ANY reason, we sincerely urge you to take advantage of our "No-Hassle", "No Questions Asked", "No Time Limit", "No Fine Print" Refund Policy. Simply call our U.S. based Customer Service Team at (858) 356-5980 and your Refund will be processed quickly and respectfully...it's really that simple.
PENETREX® is a very effective product which can be of immeasurable value to those who need it. The people who developed PENETREX® don’t want ANYONE who is suffering to miss out on discovering PENETREX® because of initial skepticism or fear of "buyer’s remorse". -
Thanks to overwhelming demand, the 2-Ounce Jar of PENETREX® is now available in Walmart & CVS stores nationwide.
Click here to find a store near you.